Anti-VEGF Eye Injection

Anti-VEGF eye injections are a treatment for macular degeneration & diabetic retinopathy

Lucentis eye injection treatment for macular degeneration and vein occlusion

Wet macular degeneration is one of the most common causes of blindness, anti-VEGF eye injection is a treatment.

Anti-VEGF eye injection is a modern treatment for wet AMD, which develops in about 1 in 10 cases of macular degeneration. Above is a video explaining how Anti-VEGF eye injection is used to treat wet macular degeneration. There are two types of macular degeneration: dry and wet macular degeneration. In the wet form of AMD, abnormal blood vessels grow in the back of the eye. Sometimes these vessels leak blood or fluid that causes blurred vision or distorted vision. Without treatment, vision loss may be quick and severe.

The patient should consult their retina specialist / ophthalmologist about signs and symptoms of Anti-VEGF side effects. Eye injections drugs are given by an eye surgeon. It is better and more effective than traditional laser eye surgery because it does not leave scarring in the macular central portion of vision.

Anti-VEGF side effects

Anti-VEGF eye injection for treatment of macular degeneration and diabetic retinopathy has few and rare side effects. The possibility of infection is extremely important to understand and the patient should consult their retina specialist / ophthalmologist about signs and symptoms of Anti-VEGF side effects.

Other uses for Anti-VEGF eye injection

More recently, Anti-VEGFs were approved for retinal vein occlusion and diabetic macular edema. These are two eye conditions that can cause profound vision loss. Adding Anti-VEGF eye injection to the vitreo-retina doctor’s arsenal is a big advancement in the retina eye care field.

Diabetic macular edema is one of the leading causes of vision loss in the world. It is caused by weakened and leaky capillaries in the retinal vascular system, due to diabetes.

Retinal vein occlusion can also cause macular edema. This condition, also known as cystoid macular edema, as responded well to Anti-VEGF eye injection. Anti-VEGF are now a mainstream treatment for these two eye conditions.

Eye injection fo macular degeneration treatment

Eye injection treatment for macular degeneration and other eye diseases

Avastin treatment for macular degeneration

Eye injection side effects and complications

Anti-VEGFs are drugs that treat eye conditions like macular degeneration, diabetic macular edema and retinal vein occlusion. Some of these drugs were first FDA approved for cancerous tumor treatment but ophthalmologists quickly discovered their promise for the treatment of leaking blood vessels caused by many common eye diseases. Eye doctors are using some of these drugs “off-label” ever since. Since some are not FDA approved for use in the eye, their intraocular use is considered off-label. However, they are now a mainstream treatment for wet macular degeneration and diabetic macular edema.

Many “mainstream” treatments are done off-label – some examples are Aspirin, Botox and many of the common depression treatments.

Eye injection side effects

Although quite rare, some complications and side effects of eye injections are being reported. Virtually every single intraocular medication has a risk of side effects. We will attempt to cover complications in this eye injections side-effects article.

Let’s look at those initial eye injection side effects:

Eye injection side effects and risks

Since the beginning of mainstream injections into the eye, the occurrence of side effects and complications from them are low.

In most cases, a patient who receives anti-VEGFs for an eye disease is in overall better health than a cancer patient – this would presumably reduce the risk of side effects, just on the basis of whole body health.

The head-to-head data comparing similar IV medications with intraocular medication side effects show the anti-VEGF given into the eye has none of the side effects of the IV treatments.

Most common eye injection side effects

After more than 17 years of using intraocular anti-VEGFs, ophthalmologists see a very small amount of side effects. However, these are the most common eye injection complications seen:

  • Red, irritated eye
  • Bloodshot eye
  • Small specks or bubble shapes in vision
  • Elevation in eye pressure
  • Tearing

Here are some very uncommon eye injection complications:

  • Inflammation inside the eye
  • Cataract
  • Retina or vitreous bleeding
  • Retinal detachment
  • A decrease in eye pressure
  • Cornea problems
  • Intraocular infection (endophthalmitis)

Allergic reaction to eye injections

Any medication has the potential to cause allergic reactions in a small number of people. Symptoms of an allergic reaction can include a rash, hives, itching, shortness of breath, and rarely, death (extremely rare). If you have allergies to other medicines, foods, or other things in the environment, or if you have asthma, you should let your ophthalmologist or his staff know. Being prone to allergies could be a red flag for your doctor to choose a different mode of treatment.


Please understand that this page is NOT to be taken as medical advice. You should speak to your medical doctor and/or ophthalmologist about any concerns or possible side effects or complications from anti-VEGFs or any other eye medication. assumes no responsibility in terms of the accuracy of this content. All information on this website is certainly not intended to replace or even augment the relationship between a patient/site visitor and his/her physician. JirehDesign makes no claims to medical/surgical/anatomical accuracy of the images on this website. The images are not to be used for medical advice.